Skip to main content

Periodontal Disease and Systemic Inflammation in Dogs

Published on August 17, 2016 for the Companion Animal Clinic

Enrollment for this study has completed. We appreciate your interest in our work.

Dentists and veterinarians at Midwestern University are working together to study the effects of periodontal disease in dogs

  • Plaque and tartar combine with bacteria along the gum-line causing a local inflammatory response in the mouth of dogs with periodontal disease.
  • In people, periodontal disease is associated with wide-spread (systemic) inflammation that can be associated with other diseases.
  • Investigators at MWU seek to determine if periodontal disease in dogs is similarly associated with systemic markers of inflammation and if routine dental treatments can reduce these effects over time.

If your dog needs a dental cleaning, he/she may qualify to participate in this study.

To qualify for participation, your dog must:

  • Be between 2 and 8 years of age
  • Weigh more than 5kgs (11 lbs)
  • Have dental disease of Grade 2 and be in need of dental treatment

Dogs will not be eligible for participation if:

  • They have any other diseases that cause inflammation
  • Are pregnant or nursing
  • Require tooth extractions

Study Procedures

Dogs enrolled in the study will have samples of blood drawn to assess their overall health and measure markers of inflammation approximately one month before dental treatment, at the time of their dental treatment, 2 weeks after dental treatment, and 1 month after dental treatment. You will be asked to complete a questionnaire about your dogs oral health care at each of these (4) visits.

Study Images



Contact Us For More Information

Dr. Angela Mexas


Christine Wills


Midwestern University Animal Health Institute Logo